Fri, 18 December 2020
For years studies have questioned whether pulse oximeters perform as well in non-White patients as in White patients. This is particularly important now as disposition decisions in patients with COVID-19 are often made based on pulse oximetry readings. We discussed an article by Sjoding et al in NEJM Show notes at FOAMcast.org Thanks for listening! |
Wed, 9 December 2020
Despite multiple Phase II/III vaccine trials of >30,000 participants, pregnant patients or those who are lactating have been largely excluded. In this podcast, we cover what we know (and what we don't know thus far). The Pfizer BNT162b2 trial data submitted for FDA Emergency Use Authorization does include information on a minuscule number of patients who were immunized and became pregnant. The Society for Maternal and Fetal Medicine has released statements on vaccines in SARS-CoV-2. In the United Kingdom, Public Health England has released guidance for their population on vaccination in pregnancy and breastfeeding which are rooted in the lack of data. Shownotes: FOAMcast.org Thanks for listening! |
Sun, 29 November 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* Vaccines for SARS-CoV-2 have been in development for only a few months, but several have published early results from Phase III efficacy trials in press releases. In this episode, we review these vaccines and what we know about them, and what we know about them Show notes (references/graphics): FOAMcast.org Thanks for listening,
Direct download: foamcast_covid_vaccine_interim_updates_.mp3
Category:general -- posted at: 10:30pm EST |
Fri, 27 November 2020
In this episode, we review cannabinoid hyperemesis syndrome and two recent randomized controlled trials on treatments
Show notes (references, graphics) at FOAMcast.org Thanks for listening! Jeremy Faust and Lauren Westafer |
Sat, 24 October 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* Monoclonal antibodies have received significant attention over the past month and we previously podcasted on antibodies that target SARS-CoV-2. In this episode, we review several recent studies on a different "mab", tocilizumab, which targets inflammation mediated by interleukin-6 that is overly ramped up. We review: Stone et al ( RCT) Salvarani et al. (RCT) STOP-COVID (observational) Show notes (references/graphics): FOAMcast.org Thanks for listening,
Direct download: FOAMcast_Covid_tocilizumab_and_covid.mp3
Category:general -- posted at: 10:30pm EST |
Sun, 11 October 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* Monoclonal antibodies have received significant attention over the past couple of weeks. In this episode, we review what we know, as of October 9, 2020, about monoclonal antibodies as a therapy for COVID-19. Show notes (references/graphics): FOAMcast.org Thanks for listening, |
Fri, 9 October 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* We review a retrospective evaluation of COVID-19 infections in employees after a protocol that increased the use of high flow nasal cannula (Westafer et al) Show notes (references/graphics): FOAMcast.org Thanks for listening, |
Mon, 21 September 2020
We spoonfeed you a new article on risk stratification of pulmonary embolism (with critical appraisal pearls!) In this episode, we review a new trial by Barnes et al on antacids versus antacids with lidocaine for epigastric pain and dyspepsia Show notes and references at FOAMcast.org Thanks for listening, Lauren Westafer and Jeremy Faust |
Thu, 3 September 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* We review a new meta-analysis from the WHO REACT group of steroids in critically ill patients with COVID-19 and 3 new randomized trials of steroids in COVID-19 published in JAMA on September 2: Show notes (references/graphics): FOAMcast.org Thanks for listening, |
Tue, 25 August 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* We review the evidence, to date, on convalescent plasma for the treatment of COVID-19. This includes 3 randomized trials, as well the US experience with >35,000 patients treated with convalescent plasma, a noncontrolled study by Joyner et al [pre-print]. Show notes (references/graphics): FOAMcast.org Thanks for listening,
Direct download: covid_convalescent_ii_-_82620_11.02_AM.mp3
Category:general -- posted at: 7:27pm EST |
Mon, 24 August 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* We review Spinner et al in JAMA 2020, an open label trial of remdesivir 5 days vs remdesivir 10 days vs 'standard of care' for the treatment of #COVID19 Show notes: FOAMcast.org Thanks for listening, |
Tue, 18 August 2020
We review the Ascorbic Acid, Corticosteroids, and Thiamine in Septic Shock (ACTS) Trial by Moskowitz et al in JAMA Show notes: FOAMcast.org Thanks for listening! |
Tue, 4 August 2020
We review the AAAAI 2020 anaphylaxis guideline (Shaker et al) A lightening review of anaphylaxis, follow by a discussion of biphasic reaction and the role of steroids and antihistamines Thanks for listening, Jeremy Faust and Lauren Westsafer |
Thu, 16 July 2020
Introducing a new series of quick, spoonfed literature updates, 1 article at a time In this episode we review a new trial by Warren et al on antacids versus antacids with lidocaine for epigastric pain and dyspepsia Show notes and references at FOAMcast.org Thanks for listening, Lauren Westafer and Jeremy Faust |
Thu, 16 July 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* We review the RECOVERY trial results on hydroxychloroquine for COVID-19 [pre-print by Hornby et al] Show notes: FOAMcast.org Thanks for listening, |
Mon, 22 June 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* We review the RECOVERY trial results on dexamethasone for COVID-19 [pre-print by Hornby et al] Show notes: FOAMcast.org Thanks for listening, |
Fri, 19 June 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* We explore effects of sterilization and re-use on N95s and KN95s efficiency and fit Sterilization of N95s and KN95s with Hydrogen Peroxide and Chlorine Dioxide (Cai et al) Extended use/reuse of N95 and fit test failure (Degesys et al) Show notes: FOAMcast.org Thanks for listening, *Recorded June 19, 2020 |
Fri, 12 June 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode we discuss data on when SARS-CoV-2 began being detected in US communities (Jorden et al)
Show notes: FOAMcast.org Thanks for listening, *Recorded June 9, 2020 |
Wed, 10 June 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode we discuss some of the mental health ramifications of COVID-19 and the lockdowns: US ED visits for mental health (Smalley et al) Mental health of children during lockdown Xie et al Psychological distress in US adults (McGinty et al) Mood and violence in Chinese interns (Li et al) Show notes: FOAMcast.org Thanks for listening, *Recorded June 9, 2020 |
Fri, 5 June 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In an update to the Convalsecent plasma episode we now cover the first RCT on the topic, Li et al Show notes: FOAMcast.org Thanks for listening, *Recorded June 4, 2020 |
Mon, 1 June 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode reviews a study published by Mehra et al in the Lancet with concerning methods and data anomalies, leading to the possibility and likelihood of falsified data. This came to light after an open letter by Watson et al detailing major issues. The Lancet issued a correction, which did not address many of the major issues and resulted in significant changes to Table S3 in the supplement. Concerningly, this group also authored the NEJM study on ACE-I/ARBs in COVID-19. Note: This is an evolving story Show notes: FOAMcast.org Thanks for listening, *Recorded June 1, 2020 |
Sat, 30 May 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode reviews a study published by Goldman et al dissecting a study on remdesivir - 5 day vs 10 day course. Show notes: FOAMcast.org Thanks for listening, *Recorded May 30, 2020 |
Sat, 30 May 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode reviews a study published by Wang et al that received incredible press coverage for touting benefits of mask wearing in one's own home....if it started prior to symptoms. This study is problematic, and we discuss why. Show notes: FOAMcast.org Thanks for listening, *Recorded May 29, 2020
Direct download: covidcast_mask_at_home_-_53020_10.10_AM.mp3
Category:general -- posted at: 10:11am EST |
Sun, 24 May 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode reviews the NIAID trial, ACTT-1, on remdesivir vs placebo (Beigel et al) Show notes: FOAMcast.org Thanks for listening, *Recorded May 23, 2020 |
Fri, 22 May 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode reviews an article by Groß et al that demonstrates SARS-CoV-2 RNA can be found in breastmilk Show notes: FOAMcast.org Thanks for listening, *Recorded May 22, 2020 |
Fri, 22 May 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19. *Our understanding of COVID-19 is rapidly developing and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode reviews an article by Peyrony et al examining the performance of symptoms, physical exam findings, and ultrasound on the probability of COVID-19. We also go into a bit of an interlude on likelihood ratios Show notes: FOAMcast.org Thanks for listening, *Recorded May 22, 2020 |
Fri, 15 May 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode is a literature potpourri
Show notes: FOAMcast.org Thanks for listening, *Recorded May 15, 2020 |
Sat, 9 May 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode discusses We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode discusses Pediatric Multisystem Inflammatory Syndrome Temporally Associated with COVID-19 , including the study published in the Lancet by Riphagen et al Show notes: FOAMcast.org Thanks for listening, *Recorded May 6, 2020 Show notes: FOAMcast.org Thanks for listening, *Recorded May 9, 2020 |
Sat, 9 May 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode discusses convalescent plasma, specifically a recent systematic review by Rajendran et al
Show notes: FOAMcast.org Thanks for listening, *Recorded May 6, 2020 |
Sun, 3 May 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode discusses antibody testing including
Show notes: FOAMcast.org Thanks for listening, *Recorded May 2, 2020 |
Thu, 30 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode discusses an article by Baldi et al on excess mortality and Out of Hospital Cardiac Arrest Show notes: FOAMcast.org Thanks for listening, *Recorded 4.29.20 |
Tue, 28 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode discusses cutaneous manifestations of COVID-19 including "COVID toes" And the more serious lesions Show notes: FOAMcast.org Thanks for listening, *Recorded 4.28.20 |
Mon, 27 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode discusses autopsy findings and VTE Show notes: FOAMcast.org Thanks for listening, *Recorded 4.26.20 |
Fri, 24 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* This episode discusses an article by Caputo et al. on self proning and oxygenation in COVID-19 Show notes: FOAMcast.org Thanks for listening, *Recorded 4.23.20 |
Tue, 21 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode, Dr. Rory Spiegel (@EMNerd_) and I discuss the "switch" from early intubation to aggressive non-invasive modalities and our respiratory protocols including what we know about the evidence behind...
Show notes: FOAMcast.org Thanks for listening, *Recorded 4.17.20
Direct download: Covid_4.19_resp_protocol_-_42020_8.17_PM.mp3
Category:general -- posted at: 6:53pm EST |
Sat, 18 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode, we discuss thrombosis and COVID-19, specifically:
Show notes: FOAMcast.org Thanks for listening, *Recorded 4.18.20 |
Fri, 17 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode, we discuss special populations including
Show notes: FOAMcast.org Thanks for listening, *Recorded 4.17.20 |
Tue, 14 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode, we discuss testing issues
And hydroxychloroquine updates
Show notes: FOAMcast.org Thanks for listening, *Recorded 4.14.20 |
Mon, 13 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode, we discuss outcomes from NYU Show notes: FOAMcast.org Thanks for listening, *Recorded 4.12.20 |
Sun, 12 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode, Dr. Rory Spiegel (@EMNerd_) and I discuss risk stratification tools in COVID-19 Show notes: FOAMcast.org Thanks for listening, *Recorded 4.10.20 |
Fri, 10 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode, we discuss the NEJM article by Grien et al on the compassionate use of remdesivir in COVID-19 Show notes: FOAMcast.org Thanks for listening, *Recorded 4.10.20 |
Tue, 7 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode, we are joined by Dr. Rory Spiegel (EMNerd) and discuss what we are seeing in COVID-19 and various theories.
Show notes: FOAMcast.org Thanks for listening, *Recorded 4.5.20 |
Sun, 5 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check back for updates/fact check what you hear* In this episode, we are joined by Dr. Rory Spiegel (EMNerd) and discuss the ROX index predicting failure of HFNC and any applicability to COVID-19
Show notes: FOAMcast.org Thanks for listening, Recorded 4.5.20 |
Sat, 4 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* In this episode, we discuss emerging evidence for high flow nasal cannula
Show notes: FOAMcast.org Thanks for listening, Recorded 4.3.20 |
Thu, 2 April 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* In this episode, we discuss the theory (there is no great evidence) of hypercoagulability in severe COVID-19 Show notes: FOAMcast.org Thanks for listening, Recorded 4.2.20 |
Tue, 31 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* In this episode, we cover
Show notes: FOAMcast.org Thanks for listening, Recorded 3.31.20 |
Mon, 30 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* Recorded 3.30.20 In this episode, we cover
Show notes: FOAMcast.org Thanks for listening, |
Sat, 28 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* Recorded 3.28.20 In this episode, we cover
Show notes: FOAMcast.org Thanks for listening, |
Fri, 27 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* Recorded 3.27.20 In this episode, we cover
Show notes: FOAMcast.org Thanks for listening, |
Thu, 26 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* Recorded 3.25.20 In this episode, we cover
Show notes: FOAMcast.org Thanks for listening, |
Tue, 24 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* Recorded 3.23.20 In this episode, we cover
Show notes: FOAMcast.org Thanks for listening, |
Mon, 23 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* In this episode, we cover
Recorded 3.22.20 Show notes: FOAMcast.org Thanks for listening, |
Sat, 21 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* In this episode, we cover
Show notes: FOAMcast.org Thanks for listening, |
Fri, 20 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. So, check us* In this episode, we cover the Society of Critical Care Medicine, Surviving Sepsis Guidelines for COVID-19 Show notes: FOAMcast.org Thanks for listening, |
Fri, 20 March 2020
We interrupt our normal FOAMcast episodes to bring you updates from COVID-19, as literature develops. *Things change frequently and this may be out of date in days/weeks. In this episode we review:
Show notes: FOAMcast.org Thanks for listening! |
Thu, 19 March 2020
We are going to try to bring you updates regarding COVID-19 on a regular basis. These podcasts will likely be out of date in a few days, so check back for updates. This episode features:
Recorded 3.18.20 Thanks for listening, Lauren Westafer and Jeremy Faust |
Sun, 8 March 2020
We review the evaluation and management of Community-Acquired Pneumonia (CAP) as well as the Infectious Disease Society of America (IDSA) / American Thoracic Society (ATS) 2019 guidelines for CAP. Shownotes and references at FOAMcast.org Thanks for listening!
Direct download: FOAMcast_community_acquired_pna_-_3_8_20_6.48_PM.mp3
Category:general -- posted at: 4:39pm EST |
Fri, 31 January 2020
We cover some top articles of 2019, including the following: Roc vs Sux: Guihard B et al. Effect of rocuronium vs succinylcholine on endotracheal intubation success rate among patients undergoing out-of-hospital rapid sequence intubation: A randomized clinical trial. JAMA 2019 Dec 17; 322:2303. (https://doi.org/10.1001/jama.2019.18254) Targeted Temperature Management after Cardiac Arrest: Lascarrou JB, Merdji H, Le gouge A, et al. Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm. N Engl J Med. 2019. Pulmonary Embolism - a new D-dimer cut off Kearon C, De wit K, Parpia S, et al. Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability. N Engl J Med. 2019;381(22):2125-2134. Pulmonary Embolism in Pregnancy: Van der pol LM, Tromeur C, Bistervels IM, et al. Pregnancy-Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism. N Engl J Med. 2019;380(12):1139-1149. TXA in head injury The CRASH-3 Trial Collaborators. Effects of Tranexamic Acid on Death, Disability, Vascular Occlusive Events and Other Morbidities in Patients with Acute Traumatic Brain Injury (CRASH-3): A Randomised, Placebo-Controlled Trial. Lancet 2019
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Fri, 17 January 2020
The VITAMINS trial by Fujii et al has been published in JAMA and provides insight into the performance of the "metabolic cocktail" (Vitamin C + thiamine + hydrocortisone) in ICU patients with septic shock. We review this trial in the context of prior literature. Show notes and references at FOAMcast.org Thanks for listening! |